Tuesday, April 30, 2013

Now, a Chewable Brain Chemical

Citicoline is a brain chemical that occurs naturally in the body.

Citicoline was originally developed in Japan for stroke.

A metanalysis performed by Mario Fioravanti and Ann E Buckley on the entire database available in 2006 from the clinical studies performed with citicoline points to its effectiviness as a treatment for patients with memory problems

Another clinical review by Secades JJ and Lorenzo JL found no serious side effects occurred in any series of patients treated with citicoline, which attests to the safety of treatment with citicoline.

Citicoline is now available as a dietary supplement to help improving memory, mental alertness and learning performance.

How does Citicoline work?

Citicoline stabilises cell membranes, restoring its lipid structure. It also stimulates the release of dopamine neurotransmitters in the brain. Citicoline might also decrease brain tissue damage when the brain is injured.


Fioravanti M, Buckley AE. Citicoline (Cognizin) in the treatment of cognitive impairment. Clin Interv Aging. 2006 September; 1(3): 247–251.

Click HERE to read the full article.

Secades JJ, Lorenzo JL. Citicoline: pharmacological and clinical review, 2006 update. Methods Find Exp Clin Pharmacol. 2006 Sep;28 Suppl B:1-56.

Alvarez-Sabín J, Román GC. Citicoline in vascular cognitive impairment and vascular dementia after stroke. Stroke. 2011 Jan;42(1 Suppl):S40-3. Click HERE to read the full article.


Commercial Citicholine is the product of an enzymatic process derived from a combination of two microorganisms but protein is not detectable in the final product.

Click HERE for the 2012 Safety Assessment on Citicoline by the Food Safety Authority of Ireland

Now, citicoline is available in Malaysia as MemoMax Chewable Tablet suitable for both Adults and Children.

Each MemoMax Chewable Tablet contains 60mg of cticoline with 48mg of a blend of several vitamins and minerals.

Adults should chew one tablet after meal, twice a day, while children only need a single daily dose.

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