Sunday, June 12, 2011

Apakah Sedut Lemak (liposuction) Menghilangkan Lemak Selamanya?

Sumber gambar : http://3.bp.blogspot.com


Sedut lemak kedengaran seperti jawapan untuk kebanyakan wanita - dan lelaki: suatu penyelesaian pantas bagi mereka yang tidak dapat menurunkan berat badan dengan diet atau senaman, atau terlalu malas untuk melakukan salah satu darinya.

Tetapi apakah lemak kembali semula?

Sebuah kajian baru-baru ini oleh Teri L. Hernandez dan Robert H. Eckel di Sekolah Perubatan Universiti Colorado mendapati bahawa pada akhirnya lemak kembali semula dalam masa satu tahun, dan tersebar ke kawasan lain dari tubuh, terutama perut bahagian atas. Ada penyebaran lebih lanjut di sekitar bahu dan trisep pada lengan.

"Fakta bahawa lemak dikembalikan sangat menarik bagi kita sebagai saintis. Ini menyokong idea bahawa paras lemak dalam tubuh sangat berkaitrapat ditetapkan oleh mekanisma yang belum ditemukan," kata Eckel. "Ini adalah hipotesis yang kami uji dan telah disahkan. Pada tikus, ketika lemak telah dibuang, ia kembali semula, dan setelah penurunan berat badan pada manusia, kebanyakan orang kembali ke berat badan asal. Kami berpendapat otak mengawal berapa banyak lemak diperlukan dalam badan dan bertindakbalas mengatur berat badan. Sebab itulah mencegah obesiti sangat penting .. "

Penyelidik 'Obesity' mengatakan bahawa mereka tidak terkejut jika lemak kembali. Data di dalam model haiwan telah menunjukkan bahawa setelah operasi pembuangan lemak, ia cenderung untuk kembali ke kawasan lain. Penyelidikan sedut lemak yang dilakukan di Universiti Colorado merupakan percubaan rawak terkawal yang pertama pada manusia.

Rujukan Jurnal:


Teri L. Hernandez, John M. Kittelson, Christopher K. Law, Lawrence L. Ketch, Nicole R. Stob, Rachel C. Lindstrom, Ann Scherzinger, Elizabeth R. Stamm, Robert H. Eckel. Fat Redistribution Following Suction Lipectomy: Defense of Body Fat and Patterns of Restoration. Obesity, published online on 7 April 2011; DOI: 10.1038/oby.2011.64


Friday, June 10, 2011

Zestz for LAUGHS?

Original author unknown.

Lakmali of Penang says "Cheer up, talk to your doctor or pharmacist today!"

Alcohol Hangover Headache


Picture credit: http://inlinethumb20.webshots.com

Researchers at Thomas Jefferson University in Philadelphia suggest aspirin and coffee are actually the best cure for veisalgia cephalgia or hangover headache.

Before this, caffeinated drinks were nor recommended because they may cause further dehydration through diuresis; and aspirin and other anti inflammatory painkillers were advised against because they irritate the stomach lining and could cause further stomach upsets after a night when you have already over indulged.

Professor Michael Oshinsky and colleagues at the Thomas Jefferson University found that the combination of caffeine and anti-inflammatory ingredients found in most pain relievers react “against the chemical compounds of ethanol, or pure alcohol.” They tested tested the effect of low doses of ethanol – about the equivalent of a single drink – on rats prone to migraines. Because low doses of alcohol typically cause headaches in migraine sufferers, this allowed them to study an alcohol-induced headache without the complication of intoxication.

Sure enough, 4 to 6 hours after imbibing, the skin around the rats' eyes became sensitive to touch, a sign they had a headache.

None of the commonly cited causes of hangovers - congeners, dehydration, or the ethanol metabolite acetaldehyde - could have caused this response, says Oshinsky. The rats were not dehydrated and they received pure ethanol. Nor did they get a headache from acetaldehyde build-up, which has been blamed for causing hangover headaches because the rats were given drugs to block conversion of acetaldehyde into acetate. In contrast, rats given acetate directly developed signs of a headache.

Caffeine and over-the-counter anti-inflammatory drugs, block some of the effects of acetate, and this may be one reason they give relief. If so, says Oshinsky, the best time to take them would be about 4 hours after drinking, when acetate levels begin to spike.

You will be further pleased to know that Lieberman HR et al had, in 1987, demonstrated that the addition of caffeine to aspirin, in a dose commonly employed in over-the-counter drugs, has significant beneficial consequences with respect to mood and performance.

If you are suffering from gastrointestinal disease including gastritis and peptic ulceration, forget caffeine and aspirin or any other NSAIDS (non-steroidal anti-inflammatory drugs) for hangover headache. In fact you should not indulge in heavy drinking in the first place. And this applies to all of us, really!

Over indulgence can seriously affect your health, judgment and can get you into a lot of trouble. Drink in moderation if you have to, it may be even good for your health! In fact, two Spanish doctors, Ramon Estruch and Rosa Lamuela, after having tested twelve hundred and fifty males and females aged of fifty and above, claimed that drinking up to a pint of beer a day is good for your health and can diminish the threat of type 2 diabetes and high blood pressure.

A final word: If you drink, do it in healthy moderation and with responsibility!*

References:

Maxwell CR, Spangenberg RJ, Hoek JB, Silberstein SD, Oshinsky ML. Acetate causes alcohol hangover headache in rats. PLoS One. 2010 Dec 31;5(12):e15963.

Estruch R, Lamuela-Raventós RM. Alcohol, wine and cardiovascular disease, two sides of the same coin. Intern Emerg Med. 2010 Aug;5(4):277-9. CLICK HERE for further discussions with on the rats.

Lieberman HR, Wurtman RJ, Emde GG, Coviella IL. The effects of caffeine and aspirin on mood and performance. J Clin Psychopharmacol. 1987 Oct;7(5):315-20.

Congeners: byproducts of fermentation in some alcohol.

* See our previous video and write up on Drink-Driving

Monday, June 6, 2011

"Selamat Malam. Tidur Yang Lena. Jangan Biarkan Pijat Menggigit"


Gambar kredit: http://subwayblogger.com/

Kemunculan kembali pijat ke seluruh dunia.

Salah satu alasan yang sering dikaitkan dengan peningkatan pijat di tempat tidur adalah kerana hadirnya berjuta-juta tetamu dan pekerja non-tetamu di negara kita dan juga meningkatnya jumlah perjalanan yang dilakukan – pijat melekat dan sangkut pada bagasi kita. Kurangnya kesedaran dan tindakan pencegahan serta menukar produk kawalan hama dan kaedah yang digunakan juga menjadi punca kepada peningkatan tersebut. Beberapa saintis berpendapat bahawa serangga juga menjadi resisten terhadap racun perosak.

Pijat mudah dilihat: Anda tidak perlu memakai kanta pembesar atau peralatan pengesanan yang canggih, hanya dengan mata kasar. Ia adalah serangga bersayap, mempunyai saiz dan warna yang hampir sama dan kelihatan seperti biji epal.

Pijat mendapat makanan dari darah manusia, tapi biasanya ia tidak membawa penyakit. Namun, sesetengah orang mempunyai alahan kepada mereka. Pijat berukuran sebesar beras ini memberikan gigitan yang menyakitkan, yang boleh menyebabkan jangkitan.
Kulit di sekitar kawasan gigitan biasanya menjadi bengkak dan sangat gatal. Ia sangat aktif pada waktu awal pagi.

Pijat mungkin bersembunyi di tempat-tempat seperti di dalam dan sekitar tempat tidur, di celah-celah belakang bantal kerusi dan sofa, dan di lipatan tirai, kerana dekat dengan bekalan makanan mereka iaitu: manusia.

Cadangan Bagi Mencegah Pijat di Rumah:

1. Jika anda menerima perabot terpakai, periksa dengan teliti jika terdapat pijat pada perabot tersebut sebelum membawa pulang.
2. Bungkus tilam dengan pelindung tertutup. Kerap memeriksa bungkusan untuk mencari jika terdapat lubang.
3. Bersihkan rumah yang berselerak bagi mengurangkan tempat persembunyian pijat.
4. Ketika pulang dari perjalanan, selongkar beg pakaian anda terus ke dalam mesin basuh. Juga periksa bagasi anda.
5. Ketika di hotel, simpan beg pakaian di rak bagasi dan bukannya di lantai. Periksa ruangan jika terdapat pijat yang berwarna coklat, berbentuk oval, dan 1 perempat hingga 3 perlapan inci panjang.

KLIK DI SINI untuk keterangan lebih lanjut mengenai pijat.

Night Owls at Risk for Weight Gain and Bad Diet


Picture credit: http://arch1design.com

Staying up late every night and sleeping in is a habit that could put you at risk for gaining weight. Now, a study has demonstrated a relationship between the timing of feeding and weight regulation.

According to Kelly G. Baron et al, people who go to bed late had shorter sleep duration, later sleep onset and sleep offset and meal times. They also eat more calories in the evening, more fast food, fewer fruits and vegetables and weigh more than people who go to sleep earlier and wake up earlier.However, the researchers are uncertain if late sleepers consume the extra calories because they prefer more high-calorie foods or because there are less healthful options at night

The extra daily calories can mean a significant amount of weight gain -- two pounds per month -- if they are not balanced by more physical activity.

According to senior author Phyllis Zee, human circadian rhythms in sleep and metabolism are synchronized to the daily rotation of the Earth, so that when the sun goes down you are supposed to be sleeping, not eating," Zee said. "When sleep and eating are not aligned with the body's internal clock, it can lead to changes in appetite and metabolism, which could lead to weight gain."

The study suggests regulating the timing of eating and sleep could improve the effectiveness of weight management programs.

Journal Reference:

Baron KG, Reid KJ, Kern AS, Zee PC. Role of Sleep Timing in Caloric Intake and BMI. Obesity, published online before print 28 April 2011; DOI: 10.1038/oby.2011.100

Wednesday, June 1, 2011

Ubat Antidepresan dan Kolesterol Mungkin Meningkatkan Gula Darah

Agen penurun lipid pravastatin (contohnya Pravachol, Apo-Pravastatin) dan antidepresan paroxetine (contohnya Paxil, Seroxat CR, Apo-paroxetine) adalah diantara ubat yang paling banyak dipreskripsi di dunia. Interaksi yang tidak terduga antara mereka boleh mempengaruhi kesihatan umum.

Jika anda sedang mengambil kedua-dua pravastatin dan paroxetine, anda harus mengambil tahu kajian terbaru yang menemukan dua jenis ubat yang diambil secara kombinasi dilihat secara signifikan meningkatkan kadar gula darah.

Kenaikan ini paling jelas ketara di antara pesakit diabetes, dimana kadar gula darah sudah terlalu tinggi, menurut catatan penyelidik.

Pengambilan ubat secara berasingan tidak meningkatkan kadar gula darah, dan para penyelidik mengatakan mereka belum dapat menjelaskan pengaruh dari kombinasi tersebut. Kombinasi antidepresan lain dengan ubat penurun kolesterol tidak meningkatkan kadar glukosa, ini bukan 'efek pengkelasan'.

Para penyelidik di US Food and Drug Administration's (FDA's) Adverse Event Reporting System (AERS) meneliti profil kesan sampingan yang melibatkan homeostasis glukosa dan mencari isyarat cukup kuat untuk gabungan ubat dengan pravastatin dan paroxetine. Mereka mengenalpasti 135 pesakit non-diabetes yang mengambil kedua-dua ubat mendapati gula darah naik sebanyak 19 miligram per desiliter (1.0 millimol per liter) setelah rawatan bermula. Mereka juga mengenal pasti 104 pesakit diabetes di mana gula darah meningkat secara purata sebanyak 48 mg / dl (2.7 mmol. / L) ketika mengambil kedua-dua ubat.

Jika anda sedang mengambil kedua-dua pravastatin dan paroxetine, adalah munasabah untuk anda berjumpa doktor dengan segera dan lihat apakah kadar glukosa anda menjadi sukar dikawal.

"Jika ia terjadi, maka saya akan berfikir kemungkinan untuk menukar statin," kata Dr Ronald B. Goldberg., Profesor perubatan di Diabetes Research Institute of the University of Miami Miller School of Medicine.

"Pesakit diabetes mempunyai risiko kemurungan lebih tinggi; mereka semua disyorkan untuk mengambil statin," kata Goldberg. "Jadi, ia mungkin memburukkan lagi kawalan gula darah pada pesakit diabetes."

Goldberg berfikir ia terlalu awal untuk mengubah amalan klinikal berdasarkan kajian sahaja. "Hal ini perlu disahkan dalam percubaan klinikal," katanya.


Sumber:
1
. N P Tatonetti, J C Denny, S N Murphy, G H Fernald, G Krishnan, V Castro, P Yue, P S Tsau, I Kohane, D M Roden, R B Altman. Detecting Drug Interactions From Adverse-Event Reports: Interaction Between Paroxetine and Pravastatin Increases Blood Glucose Levels. Clin Pharmacol Ther advance online publication, May 25, 2011; doi:10.1038/clpt.2011.83


Does Liposuction Get Rid of That Forever?


Picture credit: http://3.bp.blogspot.com

Liposuction sounds like the answer to many women's - and men's - prayers: a quick fix for those who cannot lose weight by diet or exercise, or are simply too lazy to bother with either.

But does the fat come back?

A recent study by Teri L. Hernandez and Robert H. Eckel at the University of Colorado School of Medicine have found that the fat eventually returns within one year, and is redistributed to other areas of the body, especially the upper abdomen. There was further redistribution around the shoulders and triceps of the arms.

"The fact that fat returned is of great interest to us as scientists. It supports the idea that levels of body fat are very tightly regulated by mechanisms we have yet to uncover," said Eckel. "This was the hypothesis we were testing and it was confirmed. In rodents when fat is removed it returns, and after weight loss in humans most everyone regains the weight. We think the brain somehow knows how much fat is on board and responds in a manner to regulate that weight. That's why preventing obesity is so important."

Obesity researchers said that they are not surprised the fat came back. Data in animal models have shown that after surgical removal of fat, it tends to return to other areas. The liposuction study performed at the University of Colorado is the first randomized controlled trial in humans.

Journal Reference:

Teri L. Hernandez, John M. Kittelson, Christopher K. Law, Lawrence L. Ketch, Nicole R. Stob, Rachel C. Lindstrom, Ann Scherzinger, Elizabeth R. Stamm, Robert H. Eckel. Fat Redistribution Following Suction Lipectomy: Defense of Body Fat and Patterns of Restoration. Obesity, published online on 7 April 2011; DOI: 10.1038/oby.2011.64

CLICK HERE for more information on the adverse effect of obesity and the preactical management and control measures you can easily adopt.

CLICK HERE to read about The Truth About LIPOSUCTION by Bonnie Estridge, Daily Mail