Friday, March 25, 2011

Candazole and Candacort for TINEA

Candazole is available over-the-counter but it's best to first consult a pharmacist or doctor

Both Candazole and Candacort creams contain the active ingredient clotrimazole, which is an antifungal medicine used to treat infections with fungi and yeasts.

Clotrimazole kills fungi and yeasts by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane.

The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As clotrimazole causes holes to appear in the cell membranes, essential constituents of the fungal cells can leak out. This kills the fungi and treats the infection.

Candacort contains two active ingredients, clotrimazole and hydrocortisone.

Candacort can only be purchased under the personal supervison of a pharmacist.

Hydrocortisone reduces skin inflammation by stopping skin cells from producing various inflammation-causing chemicals that are normally released when the skin reacts to irritation. These inflammation-causing chemicals include prostaglandins and various other inflammatory substances. They cause blood vessels to widen and other inflammatory substances to arrive, resulting in the affected area of skin becoming red, swollen and itchy. By preventing these inflammatory chemicals from being released in the skin, hydrocortisone reduces inflammation and relieves its related symptoms such as redness and itchiness.

The combination of medicines in Candacort cream is used to treat fungal skin infections where symptoms of inflammation, such as itching, require rapid relief.


  1. can pregnant women use candazole on the infected area (armpit)? wud it have any impact on the baby?

  2. Hello Virac

    We are unable to confirm the cause of your problem and strongly recommend that you seek the advice of your gynaecologist or your immediate healthcare provider.

    Creams containing 1% clotrimazole, like Candazole Cream, have broad-spectrum action against fungi and yeasts. Studies have shown that clotrimazole is very poorly absorbed following dermal application or intravaginal administration to humans.

    Furthermore, the use of vaginally applied clotrimazole from the 4th month of pregnancy has not been associated with ill effects. Studies in pregnant rats with intravaginal doses up to 100 mg/kg have revealed no evidence of harm to the foetus due to clotrimazole.

    However, no adequate and well-controlled studies on vaginally applied clotrimazole in pregnant women during the first trimester (first 3 months) of pregnancy have been done.

    Taking care of your environment and your choice of clothing to prevent excessive sweating, and the use of a pH balanced cleanser are practical preventive measures you should take to prevent rashes in the folds of your body.

    We hope we have been of assistance to you. Please do not hesitate to contact us if you need more information.

  3. can one month old baby use it for diaper rash ?? its still very redness after using drapolene cream..

    1. Clotrimazole is an anti fungal cream used as a ringworm treatment in cats and dogs. This primarily involves to combating the skin conditions caused by ring worm.

  4. can i use the candacort cream on my face ?

  5. Yes, Candacort can be used to treat fungal infections on the face. But, please consult your pharmacist or doctor on the nature of your skin problem before use.