Habitually sleeping less than six hours a night significantly increases the risk of stroke symptoms among middle-age to older adults who are of normal weight and at low risk for obstructive sleep apnea (OSA), according to a study of 5,666 people followed for up to three years.
The
participants had no history of stroke, transient ischemic attack, stroke
symptoms or high risk for OSA at the start of the study. Researchers from the
University of Alabama at Birmingham recorded the first stroke symptoms, along
with demographic information, stroke risk factors, depression symptoms and
various health behaviors.
After
adjusting for body-mass index (BMI), they found a strong association with daily
sleep periods of less than six hours and a greater incidence of stroke symptoms
for middle-age to older adults, even beyond other risk factors. The study found
no association between short sleep periods and stroke symptoms among overweight
and obese participants.
"In
employed middle-aged to older adults, relatively free of major risk factors for
stroke such as obesity and sleep-disordered breathing, short sleep duration may
exact its own negative influence on stroke development," said lead author
Megan Ruiter, PhD. "We speculate that short sleep duration is a precursor
to other traditional stroke risk factors, and once these traditional stroke
risk factors are present, then perhaps they become stronger risk factors than
sleep duration alone."
Further
research may support the results, providing a strong argument for increasing
physician and public awareness of the impact of sleep as a risk factor for
stroke symptoms, especially among persons who appear to have few or no
traditional risk factors for stroke, she said.
"Sleep
and sleep-related behaviors are highly modifiable with cognitive-behavioral
therapy approaches and/or pharmaceutical interventions," Ruiter said.
"These results may serve as a preliminary basis for using sleep treatments
to prevent the development of stroke."
Ruiter
and colleagues collected their data as part of the Reasons for Geographic and
Racial Differences in Stroke (REGARDS) study, led by George Howard, PhD, of the
University of Alabama at Birmingham School of Public Health. REGARDS enrolled 30,239
people ages 45 and older between January 2003 and October 2007, and is
continuing to follow them for health changes. The study is funded by the
National Institutes of Health (NIH) National Institute of Neurological
Disorders and Stroke.
###
The
above story is based on the June 11, 2012 news release by American Academy of
Sleep Medicine.
The
abstract "Short sleep predicts stroke symptoms in persons of normal
weight" is being presented June 11 at SLEEP 2012, the 26th annual meeting
of the Associated Professional Sleep Societies (APSS) in Boston.
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